胡薇,6165cc金沙总站检测中心院长,兼省部共建草原家畜生殖调控与繁育国家重点实验室主任;复旦大学教授,博导,国家杰出青年基金获得者(2017) ;中国CDC寄生虫病所寄生虫病与媒介生物学重点实验室兼职PI,博士生导师。在Nature、Nature Genetics、Nature Communications等杂志发表SCI论文70多篇,获中国发明专利授权6项,作为负责人承担国家自然科学基金、国家重大传染病防治专项、国家基础科研专项等资助的多项国家级课题。曾获第四届中国青年女科学家奖(2007),国家自然科学二等奖(2013年,第二完成人),上海市科技进步二等奖(2017,第一完成人)等。
电子邮箱:huw@imu.edu.cn或huw@fudan.edu.cn
教育经历
1999/09-2002/07,中国预防医学科学院(现中国疾病预防控制中心),寄生虫病研究所(现寄生虫病预防控制所),博士
1993/09-1996/07,华中师范大学,6165cc金沙总站检测中心昆虫学研究所,硕士
1989/09-1993/07,华中师范大学,生物系,学士
工作经历
2020/03-至今,内蒙古大学,6165cc金沙总站检测中心,教授,博导
2012/04-至今,复旦大学,6165cc金沙总站检测中心,教授,博士生导师;中国疾病预防控制中心寄生虫病预防控制所兼职研究员;
1996/07-2012/03,中国疾病预防控制中心(原中国预防医学科学院),研究员(2006,破格);博士生导师(2012);所重点实验室主任(2008-2012)
主要研究方向
应用分子生物学与遗传学、功能基因组学、生物信息学、生态学等手段,研究人兽共患病原生物的传播扩散、遗传变异、分子进化、生殖发育、侵染过程及其与宿主的相互关系,并发展新的预防、诊断和治疗方法。
代表性论文
1. Luo F#, Yin M#, Mo X#, Sun C, Wu Q, Zhu B, Xiang M, Wang J, Wang Y, Li J, Zhang T, Xu B, Zheng H, Feng Z, Hu W*. An improved genome assembly of the fluke Schistosoma japonicum. PLoS Negl Trop Dis. 2019;13(8): e0007612.
2. Li Q#, Zhao N#, Liu M, Shen HM, Huang L, Mo XJ, Xu B, Zhang XM, Hu W*. Comparative Analysis of Proteome-Wide Lysine Acetylation in Juvenile and Adult Schistosoma japonicum. Front Microbiol, 2017, 8: 2248
3. Wang JP#, Yu Y#, Shen HM, Qing T, Zheng YT, Li Q, Mo XJ, Wang SQ, Li NN, Chai RY, Xu B, Liu M, Brindley PJ, McManus DP, Feng Z, Shi LM, Hu W* Dynamic transcriptomes identify biogenic amines and insect-like hormonal regulation for mediating reproduction in Schistosoma japonicum. Nat Commun.2017, 8:14693
4. Li Q, Wang W, Zhao N, Li P, Xin Y, Hu W*, Identification and validation of a Schistosoma japonicum U6 promoter. Parasit Vectors.2017, 10(1):281
5. Liu M,Ju C, Du XF, Shen HM, Wang JP, Li J, Zhang XM,Feng Z, Hu W*. Proteomic Analysis on Cercariae and Schistosomula in Reference to Potential Proteases Involved in Host Invasion of Schistosoma japonicum Larvae. Journal Proteome Research. 2015,14(11): 4623-4634
6. Yin MB#, Zheng H#, Su J, Feng Z, McManus DP, Zhou X, Jin L and Hu W *. Co-dispersal of the blood fluke Schistosoma japonicum and Homo sapiens in the Neolithic Age. Sci Rep., 2015, 5: 18058
7. Schistosoma japonicum Genome Sequencing and Functional Analysis Consortium, Zhou Y#, Zheng H#, Liu F#, Hu W#, Wang ZQ#, Gang L#, Ren S#. The Schistosoma japonicum genome reveals features of host-parasite interplay. Nature. 2009, Jul 16; 460(7253):345-51. (#equal contribution)
8. Liu F#, Cui SJ#, Hu W#, Feng Z, Wang ZQ, Han ZG*. Excretory/secretory proteome of the adult developmental stage of human blood fluke, Schistosoma japonicum. Mol Cell Proteomics. 2009, Jun; 8(6):1236-51.
9. Liu F#, Hu W#, Cui SJ#, Chi M, Fang CY, Wang ZQ, Yang PY, Han ZG*. Insight into the host-parasite interplay by proteomic study of host proteins copurified with the human parasite, Schistosoma japonicum. Proteomics. 2007 Feb;7(3):450-62
10. Liu F#, Lu J#, Hu W#, Wang SY, Cui SJ, Chi M, Yang Q, Wang XR, Song HD, Xu XN, Wang JJ, Zhang XL, Zhang X, Wang ZQ, Xue CL, Brindley PJ, McMauns DP, Yang PY, Feng Z, Chen Z, Han ZG*. New perspectives on host-parasite interplay by comparative transcriptomic and proteomic analyses of Schistosoma japonicum. PLoS Pathog. 2006 Apr;2(4): e29.
11. Hu W, Brindley PJ, McManus DP, Feng Z, Han ZG*. Schistosome transcriptomes: new insights into the parasite and schistosomiasis. Trends Mol Med. 2004 May;10(5):217-25.
12. Hu W, Yan Q, Shen DK, Liu F, Zhu ZD, Song HD, Wang ZJ, Rong YP, Zeng LC, Wu J, Zhang X, Wang JJ, Xu XN, Wang SY, Fu G, Xu XR, Zhang XL, Wang ZQ, Brindley, PJ, McManus, DP, Xue CL, Feng Z, Chen Z, Han ZG*, Evolutionary and biomedical implications of a Schistosoma japonicum complementary DNA resource. Nat Genet. 2003 Oct; 35(2):139-47.